Supercharged Vitamin A Serum



There’s retinol, and then there’s Intelligent Retinol. With supercharged retinol activity whilst remaining gentle on the skin, this performance-enhanced vitamin A serum is available in 3 strengths.



The lightweight yet moisturising, squalane-based serum is supercharged with retinol-booster climbazole to keep it working for longer; enhancing the anti-ageing results.



Over time, the complexion is left visibly youthful, bright and smooth, with an improved look of firmness.



Retinol (vitamin A), Climbazole, Squalane & Vitamin E

Delivery Options

Standard Delivery
£3.75 or FREE on orders over £35. Please allow 3-5 working days for delivery.


Priority Delivery
£4.95 or FREE on orders over £100. Next-Day delivery when you order before 6pm Monday to Friday (Excluding bank holidays) Shipped by DPD

Key Benefits

Intelligent Retinol Ladder
Medik8 offer progressive strengths of retinol (0.3%, 0.6%,1%) in the Intelligent Retinol TR range, for every level of retinol user. We recommend Intelligent Retinol ™ 3TR for those new to vitamin A, or as an upgrade from Night Ritual Vitamin A. From there, you can work your way up the ladder over time.


Supercharged Retinol
The Intelligent formulas are enhanced with climbazole, a proven retinol-booster. Increased retinol activity, for more power but without any added irritation.


Time Release Technology
Retinol is gradually delivered to the skin with Time Release Technology, to enhance skin comfort when using retinol while prolonging the effects overnight.


Nourishing Texture
The Intelligent Retinol serums are enriched with emollient oil squalane, which leaves the skin nourished and helps to support the integration of retinol into a skincare regime.


Looking for Even More Power?
If you’re loving retinol but looking for the next innovation in vitamin A, take a look at Crystal Retinal, our next-generation vitamin A technology using crystal encapsulated retinaldehyde.


One step closer to the active form of vitamin A than retinol and unmatched in its age-defying power, retinal can deliver results up to 11 times faster than retinol.[1] Available in 4 strengths, there is a Crystal Retinal for every level of vitamin A user.


[1] G. Seigenthaler et al., Biochemical Journal, 1990, 268, pp 371-378

How It Works

Retinol, also known as vitamin A, is often referred to as the gold standard in anti-ageing skincare. When applied to the skin, it is converted to retinoic acid, the active form of vitamin A. Retinoic acid works to help support collagen synthesis and prevent its breakdown for visibly plumper, more youthful-looking skin. It can also help to speed up the natural exfoliation process while decreasing melanin production, for a visibly smooth, more evenly toned complexion.


The results-driven serum is enriched with climbazole, a proven retinol-booster. Climbazole works by helping to block the enzyme which breaks down retinoic acid, meaning a reservoir of retinoic acid is left in the skin. This prolongs and enhances the anti-ageing effects without incurring any additional irritation.


Retinol has the potential to cause some irritation when first introducing it into a skincare regime. Time Release Technology, found in all Medik8 vitamin A products, helps to minimise irritation while maximising visible results. Our Intelligent Retinol serum protects retinol in a polymer reservoir, essentially working as a protective shield between retinol and the skin. The polymer reservoir slows down how quickly the retinol is able to penetrate into the skin, gently delivering the active into the skin throughout the night.


The Intelligent formula is delivered in a silky, squalane-infused serum. squalane is a skin-identical oil that effortlessly slips into the natural skin barrier, infusing the complexion with nightly moisture while supporting the integration of retinol into your skincare routine. By being a water-free formulation, we have secured the stability of the powerful, yet fragile retinol molecule.

How To Use

After cleansing in the evening, massage 4 drops of retinol across the face, neck and décolletage.


Follow with your regular Medik8 moisturiser. We recommend Advanced Night Restore, designed to be used after vitamin A.


Retinol application should be phased in gradually. Use twice a week for the first 2 weeks, every other night for the next 2 weeks, then every night. Consult a doctor if breastfeeding or pregnant. You should always use a sunscreen in the morning while using vitamin A.


Patch testing prior to use is advised. Refer to medik8.co/patch for an in-depth guide to patch testing.


Interested in routines & layering?

Intelligent Retinol TR features in our carefully curated regime guide, Hydration Recharge. Click the link for additional product recommendations and easy-to-follow layering advice.



The classic form of vitamin A helps to boost collagen levels and enhance the skin’s natural regenerative cycle, leaving skin looking smooth, even-toned and youthful.



Climbazole has been found to boost the activity of retinoids in the skin to give the power of higher percentages without the irritation.



A natural emollient; squalane helps to restore the skin’s natural defence barrier while deeply hydrating the skin.


Vitamin E

An oil-soluble antioxidant, vitamin E can quench free radicals on the skin while stabilising retinol for optimal power.


Full Ingredients


What we choose not to include



Used in Professional Treatments

Boost the results of Intelligent Retinol
Visit a Medik8 specialist for a detailed skin consultation and experience one of our relaxing anti-ageing facial treatments.


Rewind Professional Skin Peel
A targeted peel that helps to promote collagen production to reduce the appearance of fine lines and wrinkles. It fades away imperfections, leaving the skin visibly smoothed and rejuvenated.


Get a consultation

The Science Behind

“Climbazole is an incredible breakthrough in vitamin A technology. It has been proven to boost the activity of vitamin A by blocking the enzymes which break down retinoic acid in the skin; hence leaving a reservoir of power to supercharge results.[1] All without incurring any extra irritation; a true retinol booster.“


Daniel Isaacs, Medik8 Director of Research


[1] J. Adamus et al., Climbazole boosts activity of retinoids in skin, International Journal of Cosmetic Science, 2017, 39(4), pp 411-418

Intelligent Retinol

Intelligent Retinol 3TR™ – 15ml, Intelligent Retinol 6TR™ – 15ml, Intelligent Retinol 10TR™ – 15ml



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